More Views Of Stem Cell Transplant

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A stem cell transplant may be necessary if your bone marrow stops working and does not produce enough healthy stem cells. A stem cell transplant also may be performed if high-dose chemotherapy or radiation therapy is given in the treatment of blood disorders such as leukemia, lymphoma or multiple myeloma. A stem cell transplant can help your body make enough healthy white blood cells, red blood cells or platelets and reduce your risk of life-threatening infections, anemia and bleeding. Stem cell therapy does not fight cancer.It is also known as a bone marrow transplant, peripheral blood stem cell transplant or an umbilical cord blood transplant, depending on the source of the stem cells. Stem cell transplants can use cells from your own body (autologous stem cell transplant), from a donor (allogeneic stem cell transplant) or from an identical twin (syngeneic transplant). A mini stem cell transplant, also called reduced-intensity conditioning or a nonmyeloablative (non-my-uh-loh-ab-LAY-tive) transplant, is a type of allogeneic transplant that involves a less intense conditioning option.
Reduced-intensity conditioning, which ...
... includes lower doses of chemotherapy and radiation, kills some cancer cells and somewhat suppresses your immune system. Then, the donor's cells are infused into your body. Donor cells replace cells in your bone marrow over time. Immune factors in the donor cells may then fight your cancer cells.

The stem cells which were harvested from the patient before high-dose chemotherapy and transfused back into the patient after high-dose chemotherapy were not damaged by chemotherapy. It takes these undamaged stem cells approximately ten to fourteen days to graft to the bone marrow and begin producing new red, white and platelet blood cells.A stem cell transplant may be used so that you can have intensive high-dose chemotherapy (and sometimes radiotherapy) to kill cancerous cells. The chemotherapy is higher than conventional chemotherapy and also kills the stem cells in the bone marrow that would normally make blood cells. Therefore, following the chemotherapy, you are given back (transplanted) stem cells which can then make normal blood cells again.A stem cell transplant is sometimes called a bone marrow transplant. However, stem cells can be obtained from blood as well as from the bone marrow. So, the term stem cell transplant is now used.Stem cells are primitive (immature) cells. There are two main types in the bone marrow - myeloid and lymphoid stem cells. These derive from even more primitive cells called common pluripotent stem cells. Stem cells constantly divide and produce new cells. Some new cells remain as stem cells and others go through a series of maturing stages (precursor or blast cells) before forming into mature blood cells.A stem cell transplant is an option which is considered for various cancer conditions. The higher doses of chemotherapy and radiotherapy that can be used in conjunction with a stem cell transplant can improve the chance of a cure for some conditions in certain circumstances.# Some stem cells occur in the blood (most are in the bone marrow). The stem cells in the blood can be collected (harvested) by a machine called a cell separator. The blood flow is diverted from a vein in the arm to pass through the machine which separates out the stem cells. The procedure takes about 4-6 hours. Drugs are given for a few days before this procedure to stimulate the body to make more stem cells in the bone marrow which spill out into the blood.

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