Report On Dna Sequencing Equipment And Services Markets

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This report, DNA Sequencing Equipment and Services Markets, represents the third time Kalorama has detailed the market for DNA sequencing systems, as well as consumables used in sequencing and sequencing services. Much has changed since the last Kalorama edition of this report. More companies are offering sequencing services. The market was moving in a relatively linear manner for about two years in terms of competition, with no disruptive technologies or business models introduced. After a period of relative stability, the market has seen major developments in 2011 and 2012. The introductions of the Ion Torrent PGM, PacBio RS and MiSeq have changed the situation in the market, with more new technologies expected from Ion Torrent as well as Oxford Nanopore. http://www.bharatbook.com/biotechnology-market-research-reports/dna-sequencing-equipment-and-services-markets.html

DNA sequencing can be defined as any biochemical method for determining the order of the nucleotide bases, adenine, guanine, cytosine, and thymine, (A,G,C,T) in a DNA nucleotide. DNA Sequencing has accelerated research and discovery, which created a brisk ...
... market for sequencing systems that perform this work. TXThe growing availability of vast amounts of annotated sequence data permits life science researchers to undertake a much wider range of experiments.As part of the report’s coverage, the following data is provided: Business Report

Current Market Estimate
Historical Market Data since 2006
Forecast to 2016
Review of Major Company Sequencing Products
The Status of Next Gen Systems
Clinical Applications vs. Research Applications in Sequencing
Litigation and Intellectual Property Developments
Deals in the Industry
Market Share of Major Players
Challenges and Strategic Recommendations

It is the beginning of a revolutionary time for the life sciences. Pricing changes, purchases by first-time users. Consortia, initiatives, a Groups have been organizing to sequence hundreds or thousands of individuals, species, tumors and the like in a short period of time – the 1,000 Genomes Project, the 1,001 Arabidopsis Project, and many others, many of which are covered in Chapter 2 – Trends. Longer-term, questions still remain for broad areas that are seen as large opportunities, such as disease prevention and diagnostics.

The market remains volatile, but some patterns have been stabilizing in recent years. The report uses primary and secondary research to present market watchers with an assessment of the marketplace in 2012. As part of its coverage, the report profiles the following companies:

454 Life Sciences (Roche)
Complete Genomics
Illumina
Life Technologies
Pacific Biosciences

In the next five to ten years, the report details, any of the related areas could turn into home runs, or strikeouts, for sequencers and in general. The science is constantly evolving, and trends could work against DNA sequencers for some reason. Microarrays are still more cost-effective for GWAS, but given the trends in the science and the sequencing costs, it seems inevitable that will change. Further complicating things, somatic mutations, viral genome insertions, and epigenetic changes continue throughout life. The competition has been brutal as systems are constantly improved and new products are appearing with increasing frequency. Longer-term, new segments in diagnostics and industry are likely to open up further. The pharmaceutical industry is likely to be a growing segment, due to personalized medicine and other genomics-related projects.

CHAPTER ONE: EXECUTIVE SUMMARY
Introduction
New Systems, Services Create Uncertainty
A Period of Rapid Adoption, But Lower Prices
Further Longer-Term Challenges
Rapid Growth Overall, But Intense Competition
Customers’ Research Models Evolving
Established Next-Generation Systems Seeing Slowdown
Background
Scope and Methodology
Applications and Definitions
Types of Samples
DNA Sequencing Strategies

CHAPTER TWO: SEQUENCER MARKET TRENDS
Industry and Technology Trends
Market Fragmenting Into Multiple Product Types and Applications
Continual Improvements Expand Sequencer Market
Acquisitions and Collaborations for New Technologies
Patent Infringement, Other Legal Disputes
Slow Path to Potentially Large Clinical Markets
Spread of Targeted Enrichment, Sequence-Capture Products and Services
Synergies Appearing Between Life Science Companies’ Products
Consumer Genomics, Genetic Testing, Pharmacogenetics Still Entering Mainstream
NHGRI Funding, Budget, Periodic Strategic Planning
NHGRI Shifts Funds from Centralized Sequencing Centers
NHGRI White Paper #4: The Future of Genome Sequencing
Genome Projects and Consortia
The Cancer Genome Atlas (TCGA) Project
National Plant Genome Initiative
NSF/USDA Microbial Genome Sequencing Program

CHAPTER THREE: DNA SEQUENCING SYSTEMS AND TECHNOLOGIES
454 Life Sciences (Roche)
Genome Sequencer FLX, FLX+, Junior
Illumina
HiSeq, HiScan SQ, MiSeq, Genome Analyzer IIx
Intelligent Biosystems (Qiagen)/Azco Biotech
LI-COR Biosciences 4300
Life Technologies/Applied Biosystems
ABI Prism 310 Genetic Analyzer
ABI Prism 3100-Avant Genetic Analyzer
Applied Biosystems 3100 Genetic Analyzer
Applied Biosystems 3130 Genetic Analyzer
Applied Biosystems 3130xl Genetic Analyzer
Applied Biosystems 3500 Genetic Analyzer
Applied Biosystems 3730 DNA Analyzer
Applied Biosystems 3730xl DNA Analyzer
ABI SOLiD 4, 5500, 5500xl, 5500xl W Genetic Analyzers
Ion Torrent Personal Genome Machine (PGM)
Pacific Biosciences
PacBio RS
Technologies Under Development
Introduction
Human Microbiome Project Technology Development Awards

CHAPTER FOUR: SEQUENCING MARKET ANALYSIS
Revenues Forecast
Historical Revenues
Overall Market Forecast
Sequencing For a Clinical Purpose
Roche
ABI
Illumina
Affymetrix
B.C. Cancer Agency
Emory Genetics Lab
Bacterial and Viral Applications for NGS
eGenomics
BGI
Pacific Biosciences
Clinical Sequencing vs. Research Sequencing Markets

CHAPTER FIVE: COMPETITIVE ANALYSIS
Introduction
Benchtop and Third-Generation Sequencers Bring Instability
Second-, Third-Generation Battle Still Undefined, Unresolved
Increased Flexibility with Purchasing
ABI Capillary Electrophoresis Holds Onto Large Segment
DNA Sequencer Market Shares
Smaller Companies Experiencing Struggles
Features and Strengths of Second-Generation Sequencers
454 Life Sciences GS FLX–Strengths/Advantages
454 Life Sciences GS FLX–Weaknesses/Disadvantages
454 Life Sciences GS Junior–Strengths/Advantages
454 Life Sciences GS Junior–Weaknesses/Disadvantages
Applied Biosystems SOLiD–Strength/Advantages
Applied Biosystems SOLiD–Weaknesses/Disadvantages
Illumina HiSeq/HiScan SQ–Strength/Advantages
Illumina HiSeq/HiScan SQ–Weaknesses/Disadvantages
Illumina MiSeq - Strength/Advantages
Illumina MiSeq-Weaknesses/Disadvantages
Life Technologies PGM-Weaknesses/Disadvantages
Pacific Biosciences PacBio RS-Strength/Advantages
Pacific Biosciences PacBio RS-Weaknesses/Disadvantages

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DNA Sequencing Equipment and Services Markets

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