Types Of Tests In Clinical Trials

By Author: Rajesh Kumar
Total Articles: 17
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The clinical trial represents an important procedure for the evaluation of different aspects of health. Among them, the effectiveness of treatments, the quality of diagnosis and the study of preventive methods in a given area and its realization is categorized by offering an essential support to the specific clinical measures.



Concept and application fields of clinical trials

The clinical trial is a study method that allows medical research aimed at determining the effectiveness of a treatment or prevention related to disease processes and clarification of its safety and convenience of your application. There is a list of assays and validated methods in clinical research which are used in applying the drug testing on different objects (Animals and Humans).


Areas of application for clinical trials

Evaluation of new treatments, whether pharmacological nature or any other kind.
Investigation of systems for preventing pathological processes at ...
... the use of several procedures: medications, vaccines, lifestyle, etc.
Search diagnostic systems or screening procedures.
Study of mechanisms to improve the quality of life in people with a particular disease or health-related process.

Types of clinical trial

Among the classes of clinical trial of greater reliability and frequency of use are:

According to the temporary space at: prospective or retrospective.
As random: that is, the choice of the group of patients who participate in the study is done randomly, dividing normally in a placebo group or control group and a treatment group.
According to the mask: a double blind (neither investigator nor the patient have knowledge of whether it receives placebo or treatment) or open (the subject and the observer aware of these aspects).
According to the exhibition: cross (the patient is in various stages, both placebo and treatment study) or parallel (only applies one of two options).
Mainly the types of clinical trials combine several of these aspects in order to ensure the highest possible quality of the study.

Phases of a clinical trial

A correct clinical research performed by clinical research companies includes the following basic steps:

First phase - This section conducts a safety study, representing the first application in humans with the essential purpose of assessing signs of toxicity or the like. It is usually done with a small homogeneous group of patients.

Second stage - In this interval the patient group under study is larger, there being a party to configure the control group. This phase can be very long, even-year and aims to test the effectiveness of treatment to investigate.

Third stage - During this period, a comparative analysis is done between patients receiving the new treatment and those who have been under the administration of a placebo or other treatments.

Fourth phase - This is the stage of drug approval and surveillance, in which the treatment is monitored for the possible occurrence of toxicity or undesirable effects even after the sale or distribution of the drugs.



About Author

Choice of a good CRO for clinical trials services should be the first priority according to the author.