Evolutionaryscale Launches With Esm3: A Milestone Ai Model For Biology

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EvolutionaryScale, a renowned AI research lab in the field of biology, has recently introduced ESM3, an advanced AI model with the remarkable capability of generating unique proteins. This groundbreaking model has successfully produced a new Green Fluorescent Protein (GFP), a process that would naturally require an astonishing 500 million years of evolution. By providing scientists with interactive prompting, ESM3 empowers them to create proteins, thereby revolutionizing applications in drug discovery, materials science, and carbon capture.

The visionary team at EvolutionaryScale has been at the forefront of applying AI to biology, having previously developed ESM1, the very first transformer language model designed specifically for proteins. The ESM models have played a pivotal role in driving significant scientific advancements, particularly in the realm of protein folding, which has unveiled the intricate structures of millions of metagenomic proteins. These models have proven to be indispensable tools for scientists worldwide, enabling them to model and comprehend proteins with greater precision.

ESM3, having ...
... undergone extensive training with an impressive 1 trillion teraflops on a dataset comprising 2.78 billion proteins, stands as the pioneering generative model for biology that takes into account the sequence, structure, and function of proteins simultaneously. This remarkable capability empowers scientists to gain a comprehensive understanding of proteins and even create entirely new ones, effectively transforming biology into a programmable science. Alexander Rives, co-founder and chief scientist of EvolutionaryScale, emphasizes that ESM3 represents a significant step towards a future where AI becomes an essential tool in the field of biological engineering.

The potential of ESM3 to expedite discoveries across various domains is immense, ranging from the development of novel cancer treatments to the creation of proteins for carbon capture. By simulating 500 million years of evolution to generate a new GFP, ESM3 has demonstrated its ability to produce intricate proteins that play a crucial role in molecular biology.

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