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What To Consider When Dosing Cannabis Part 3
People frequently have no idea where to begin when it comes to dosing cannabis, particularly considering the numerous ailments for which it can be used and the fact that everyone's physiology is different. People want to know what ratio of THC to CBD they should take, which strain is best for them, and which product is most effective for treating their ailment (s).
Patients are becoming more knowledgeable with the idea of chemovariance as a result of this line of enquiry, which is a positive development in some respects. Chemovariety is a term that refers to the varied substances and ratios present in distinct cannabis strains (or, more precisely, varietals or cultivars) that may or may not be beneficial for a specific ailment. Cannabinoids, flavonoids, and terpenes are all components of the cannabis plant that contribute to its distinctive effects, which are collectively referred to as the "entourage effect." Flavonoids are responsible for the plant's tastes, and terpenes are responsible for its aroma.
On the other hand, there is a great deal more that we do not fully understand concerning the appropriate proportions ...
... of cannabis's many components for various applications. Other aspects, including age, gender, height, weight, determinants of lifestyle such as nutrition and exercise, the use of other medications, and the illness or conditions that are being suffered from, are also need to be taken into consideration. But research is expanding, and even though we don't have enough studies, patients still have some important factors to take into account when choosing profiles and strains (varieties) that might be beneficial to them.
Cannabinoid Hunting
Sometimes the marketing machine goes into overdrive, and particular cannabinoids and terpenoids become the flavor of the month. This is something that we see quite frequently. CBD is probably the best illustration of this, and many people claim they desire solely CBD with none of the psychoactive effects of THC. This method of approaching things is not supported by any scientific evidence. For instance, some patients, such as those who are afflicted with cancer or neurological diseases such as multiple sclerosis, may require THC in order to alleviate pain and/or spasms.
Additionally, when THC is absent, CBD does not perform as well as it normally would. CBD has been shown to be an effective antiemetic. When you combine it with a small amount of THC and CBDA, the CBD transforms into an even more effective antiemetic that also has less negative side effects. A sativa strain that is high in THC and contains terpenes like as limonene, pinene, and beta-caryophyllene may be beneficial for a person who suffers from ADD or ADHD. On the other hand, those who are prone to anxiety may want to steer clear of such a profile. You should not give in to effective marketing, and you should pay no attention to people who criticize THC or any other cannabinoid or terpene. There is some truth to the entourage effect.
Nevertheless, despite all of the challenges that come with "searching" for particular cannabinoids and terpenoids, certain situations do indeed respond more favorably to particular profiles. Although we do not yet have a definitive answer as to which profile is ideal for particular circumstance, we have identified some commonalities.
Keep in mind that not all products are created equal!
Do you believe that all formulations containing a ratio of 3:1 CBD:THC, or any other ratio, are the same? Not quite; different extraction procedures will probably have different effects; therefore, the creation of a product with a CBD:THC ratio of 3:1 by one firm will differ rather dramatically from that of another company. On top of any changes in extraction method, both businesses will probably use different plants to create their goods. Additionally, they may add or remove other cannabinoids and terpenoids from the preparation.
In the case of tinctures in particular, the carrier oil that is employed as a base will, to a certain extent, also alter the absorption rate. Olive oil and medium-chain triglyceride oil (MCT oil) are the two oils most commonly used because of the ease with which the body can absorb them and the possible health benefits they offer.
Even when using the same concentration of marijuana, different ingestion routes can provide very different outcomes. Keep in mind that ingesting cannabis can produce stronger effects than inhaling it, while the potency of tinctures can be comparable to that of edibles. When you need relief more quickly, vapes may be a better option than microdosing tinctures and foods, which is best for longer-term comfort. This site will teach you how to manufacture your own cannabis oil or cannabutter, and it will also provide you with more information about the benefits and drawbacks of each route of absorption.
Always keep in mind that cannabinoids have a "bilayer" structure.
This indicates that various amounts of cannabis can produce a wide variety of effects in the body.
At lower quantities, CBD may have an energizing effect, however at greater doses, it may have a sedative effect. CBG may exhibit the same kinds of behaviors.
At lower doses, THCV exhibits antipsychotic effects, but at greater concentrations, it demonstrates psychedelic properties.
THC, when taken in low dosages, can have antidepressant and anxiolytic (anti-anxiety) effects; but, when taken in higher doses, it can cause anxiety and paranoia.
Alternate terpene configurations may possibly contribute to the observed differences. Cannabis strains that are strong in myrcene, linalool, and humulene, in addition to THC, have a tendency to produce sedative effects. Cannabis strains that are lower in myrcene and higher in limonene, terpinolene, pinene, and beta-caryophyllene, have THC concentrations that are more mild and CBG concentrations that are lower are typically described as having a more uplifting effect.
We hope this information provides a helpful framework for self-discernment, even though we cannot provide definitive advice on which strain of cannabis or cannabinoid profile may be best for you, from a scientific and legal perspective. A good rule of thumb is to ease into it and work up to the point where you feel most at ease without becoming too inebriated.
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