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Is It Possible To Build Up A Tolerance To Cannabis?
Do you feel that cannabis is no longer providing the same benefits it once did? You probably have a high tolerance for cannabis, therefore it's not your imagination.
If you regularly consume cannabis, your body will develop tolerance to it. Tetrahydrocannabinol (THC), one of cannabis' psychotropic components, activates CB1 cannabinoid receptors, leading to this effect. Cannabis use causes the CB1 receptors to become less sensitive over time, diminishing the psychoactive effects of THC.
Tolerance levels can also be affected by genetics and the potency of your cannabis.
It becomes necessary to take more of the substance to achieve the same effects when this occurs.
The Pros and Cons of Getting Used to Cannabis
At first glance, developing a tolerance to THC might seem like a bad thing, but there are actually some upsides to it.
Advantages
Developing a tolerance to THC has many advantages. Possessing a high tolerance for cannabis allows you to do the following:
Use larger cannabis doses for medical purposes (e.g. reducing symptoms for a cancer patient or battling inflammation ...
... of a traumatic brain injury).
Experience less negative affects, such as nervousness, paranoia, and inebriation.
Benefit from alleviation without the side effects of drunkenness. People with chronic pain who prefer not to take opioids can benefit greatly from this.
Disadvantages
Many people go for cannabis because of the positive effects it can have on their mood, appetite, sleep, and pain levels. However, tolerance to THC can lessen these effects with time.
The list of drawbacks continues with:
Costs increased. To achieve the same high from cannabis now costs far more money.
New items need to be discovered. What cannabis products once worked for you may no longer do so, forcing you to start the search process from scratch.
Taking too much by mistake. Potential for overdosing and experiencing extreme anxiety or paranoia. Even while tolerance to THC can help folks with anxiety, taking too much at once can cause a panic attack. To lessen the likelihood of an anxiety attack, people with anxiety may find it helpful to "microdose" and avoid developing a tolerance.
Trying out new medicines is being done. If the cost of cannabis becomes prohibitive, you may be tempted to resort to stronger drugs.
Cannabinoid Tolerance Reset
When it comes to using cannabis for medical purposes, a middle ground is possible. You want to increase your tolerance so that any potential adverse effects are minimized. But you don't want to develop a tolerance so high that you have to keep increasing your expenditures to keep getting the same result, either.
Here are a few suggestions for dampening tolerance:
A Pause for Tolerance
T-breaking, or taking a break from cannabis use to reduce tolerance, is a strategy for regaining some of the drug's psychoactive effects after prolonged abstinence.
The average length of a tolerance break is between one day and 35 days. Many people take breaks from cannabis use for reasons other than wanting to prolong the euphoric effects of THC.
Even a short break of 24 to 48 hours from THC can significantly lower cannabis tolerance due to the rapid breakdown of natural, plant-based cannabinoids by the body's endocannabinoid system (ECS). It is estimated that cannabinoids like THC are eliminated from the body and return to baseline levels within a month.
If you're a medical marijuana user thinking of taking a T-Break, you should talk to your doctor first.
Reduce the amount of cannabis you're using slowly.
Skipping a dose of medical cannabis might have disastrous consequences, including seizures, for patients who rely on it. You can keep up your regular cannabis consumption while decreasing tolerance if that's a problem for you.
Observing all prescribed dosages religiously. If you find that a daily dose of 20 mg of THC combined with 10 mg of CBD effectively relieves your symptoms without producing any noticeable intoxication, you can reduce your dosage to 10 mg of CBD. Limiting your intake will lessen the likelihood that your body will develop a tolerance to the drug.
Microdosing. The best strategy to limit the likelihood of building tolerance is to start with a low dose of THC and gradually increase it until your symptoms have subsided.
Changing brands. Unfortunately, this isn't always the best option because different persons and ailments call for different formulations (e.g. autism). If you don't want your body to become too accustomed to a single product or strain/cultivar, switching up the cannabinoid and terpene profiles may help.
Substituting cannabinoids other than delta-9 THC, which do not produce intoxication. Anxiety and pain relief can be achieved with reduced psychoactivity by combining cannabidiol (CBD), cannabinol (CBN), cannabichromene (CBC), and cannabigerol (CBG). When combined with other cannabinoids, CBD can lessen their propensity to cause tolerance. This may be why many people find a 1:1 ratio of THC to CBD to be optimal.
Delta-8 THC and THCV are being utilized.
Because of its lower psychoactivity compared to delta-9 THC, delta-8 THC is sometimes used to help patients build up less of a tolerance to the latter. It has been found that low doses of THCV are anti-psychoactive and can mitigate the effects of THC, while higher doses of THCV are psychoactive and can amplify the effects of THC.
Terpenes were added. Terpenes produce results that are not like anything else. While a blend of limonene and beta-caryophyllene in high doses may have more excitatory effects, a blend of linalool, humulene, and myrcene can be very relaxing.
Cannabidiol (CBD) and other nonpsychoactive cannabinoids: is tolerance possible?
Cannabinoids like cannabidiol (CBD) are much more difficult to gauge for tolerance development than psychoactive cannabinoids like tetrahydrocannabinol (THC) (THCV). To answer your question, however: no, CBD tolerance is not a thing.
Unlike THC, CBD does not cause tolerance by binding to CB1 receptors. Tolerance to THC can be lowered because CBD "re-sensitizes" CB1 receptors by decreasing their activity.
Because of this, CBD and other cannabinoids are extremely helpful in ensuring that a patient does not develop a tolerance to a single cannabinoid, which can have serious consequences.
Finding a Cannabis Sweet Spot
Successful medical cannabis treatment requires locating the optimal dosage.
Although cannabis use can improve one's mood and alleviate some symptoms, tolerance can develop if too much is consumed at once. This is a prime example of why titrating up to a therapeutic dose of cannabinoids must be done cautiously.
Also, we suggest picking up some goods that feature a wide variety of cannabinoids and terpenes.
If you follow these guidelines, you'll have less of a chance of having a negative experience with cannabis and getting turned off from a plant that, if given the chance and proper respect, could do wonders.
If you give cannabis the same respect you'd give any other medicine, it'll take care of you.
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