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Deep Brain Stimulation (dbs) | Parkinson’s Disase
What is Parkinson's disease?
Parkinson’s disease (PD) is a neurodegenerative disorder that affects predominately dopamine-producing “dopaminergic” neurons located in a specific area of the brain called substantia nigra. It is a chronic and progressive disease that manifests as a movement disorder in the patients’ daily life.
What causes Parkinson's disease?
The Parkinson's disease starts with the loss of the brain cells that produce the dopamine which is one the body's neurotransmitters or what is are often referred to as the chemical messengers, the cell damage appears slowly and progress gradually over time, eventually the cells will die. It is estimated that between 60% to 80% of cells are damaged before clinical symptoms of the disease become evident. Therefore, the amount of dopamine decreases in brain and irregular brain activity occurs. This is how the symptoms of this disease begin to manifest.
Even if Parkinson's disease seems genetic in some cases, it often occurs randomly and its causes remains unknown until this day, however most researchers believe that there are both genetic and environmental factors that contribute to the injury and eventual the loss of these dopamine-producing cells
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